It can be alot to happen between now and 2010 but the Democrats are looking good for 2010 senate races. I see some interesting races if Arnold Schwarzenegger goes up against Barbara Boxer, Janet Napolitano against John McCain, Chuck Grassley against Tom Vilsack, Sam Brownback against Kathleen Sebelius, Judd Gregg against John Lynch, Arlen Specter against Rendell or Mathews.
In some polls already Specter looked safe against Chris Mathews but i have not seen any polls against Rendell. It showed McCain losing against Napolitano and Arnold/Boxer would be something. It is speculation on who runs against them but here is a good list for 2010. Brownback is not running again in 2010 from Kansas and usually all reps in Kansas win but Kathleen Sebelius(D) is really liked. Maybe Brownback would like to throw his hat in the presidental ring.
http://www.electoral-vote.com/
Democrats Could Gain Southern Senators in 2010
http://www.southernpoliticalreport.c..._1117_666.aspx